Novavax uses a more traditional vaccine technology, directly delivering a lab-made version of the COVID spike protein upon injection. Novavax: Authorized for adults age 12 and older. ![]() The third shot for children in that age group is the updated, omicron-specific vaccine. Both require two shots spaced apart for full primary vaccination, except for Pfizer recipients ages 6 months to 4 years, who are given three separate doses. Both Pfizer and Moderna use mRNA technology, which prompts the body to make its own version of COVID-19’s spike protein, a key part of the virus.
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